Older people more often develop adverse effects. If stopped suddenly after long-term use, benzodiazepine withdrawal syndrome may occur. Physical dependence and psychological dependence may also occur. With long-term use, larger doses may be required for the same effect. Among those who are depressed, there may be an increased risk of suicide. When given intravenously, the person should be closely monitored. Ĭommon side effects include weakness, sleepiness, low blood pressure, and a decreased effort to breathe. When given by injection onset of effects is between one and thirty minutes and effects last for up to a day. It can be given by mouth or as an injection into a muscle or vein. It is also used, along with other treatments, for acute coronary syndrome due to cocaine use. It is also used during surgery to interfere with memory formation and to sedate those who are being mechanically ventilated. It is used to treat anxiety disorders, trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication.
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